ChatRadio-Valuer: A Chat Large Language Model for Generalizable Radiology Impression Generation on Multi-Institution and Multi-System Data
Achieving clinical level performance and widespread deployment for generating radiology impressions encounters a giant challenge for conventional artificial intelligence models tailored to specific diseases and organs. Concurrent with the increasing accessibility of radiology reports and advancements in modern general AI techniques, the emergence and potential of deployable radiology AI exploration have been bolstered. Here, we present ChatRadio-Valuer, the first general radiology diagnosis large language model for localized deployment within hospitals and being close to clinical use for multi-institution and multi-system diseases. ChatRadio-Valuer achieved 15 state-of-the-art results across five human systems and six institutions in clinical-level events (n = 332,673) through rigorous and full-spectrum assessment, including engineering metrics, clinical validation, and efficiency evaluation. Notably, it exceeded OpenAI's GPT-3.5 and GPT-4 models, achieving superior performance in comprehensive disease diagnosis compared to the average level of radiology experts. Besides, ChatRadio-Valuer supports zero-shot transfer learning, greatly boosting its effectiveness as a radiology assistant, while ensuring adherence to privacy standards and being readily utilized for large-scale patient populations. Our expeditions suggest the development of localized LLMs would become an imperative avenue in hospital applications.
Authors
- Peixin Dong (ORCID: https://orcid.org/0000-0002-2335-1394)
- Zuowei Jiang (ORCID: https://orcid.org/0000-0002-8584-6376)
- Youlan Shang (ORCID: https://orcid.org/0009-0003-5227-6500)
- Jiaqi Yao (ORCID: https://orcid.org/0009-0004-7785-3295)
- Yaonai Wei (ORCID: https://orcid.org/0009-0006-5792-7677)
- Haixing Dai (ORCID: https://orcid.org/0000-0003-0409-6129)
- Zheng‐Xiang Li (ORCID: https://orcid.org/0000-0003-4350-5976)
- Ying Zeng (ORCID: https://orcid.org/0000-0003-4162-6387)
- Zhixue Zhang (ORCID: https://orcid.org/0009-0004-5424-725X)
- Lei Guo (ORCID: https://orcid.org/0000-0003-4780-712X)
- Zihao Wu (ORCID: https://orcid.org/0000-0001-7483-6570)
- Xiaoyan Kui (ORCID: https://orcid.org/0000-0002-9957-7867)
- Tianyang Zhong (ORCID: https://orcid.org/0009-0002-4124-1129)
- Lei Guo (ORCID: https://orcid.org/0000-0003-0728-896X)
- Ming Li (ORCID: https://orcid.org/0000-0002-1218-2804)
- Jun Liu (ORCID: https://orcid.org/0000-0002-7851-6782)
- Jun Liu (ORCID: https://orcid.org/0000-0003-4007-6109)
- Jiaqi Wang (ORCID: https://orcid.org/0000-0001-8841-0124)
- Shu Zhang (ORCID: https://orcid.org/0000-0002-3431-744X)
- Lei He (ORCID: https://orcid.org/0000-0001-5390-5282)
- Yiwei Li (ORCID: https://orcid.org/0000-0003-2389-3203)
- Tianming Liu (ORCID: https://orcid.org/0000-0002-8132-9048)
- Tuo Zhang (ORCID: https://orcid.org/0000-0002-6075-3384)
- Chao Zheng (ORCID: https://orcid.org/0000-0002-2779-0255)
- Hao Chen (ORCID: https://orcid.org/0000-0003-0482-8940)
- Li Yang (ORCID: https://orcid.org/0000-0001-7326-665X)
- Jiadong Zhang (ORCID: https://orcid.org/0000-0001-6305-4928)
- Zhengliang Liu (ORCID: https://orcid.org/0000-0001-7061-6714)
- Ning Zhu (ORCID: https://orcid.org/0000-0002-7535-1310)
- Yisong Wang (ORCID: https://orcid.org/0000-0001-9683-1420)
- Yifan Zhou (ORCID: https://orcid.org/0000-0002-3538-621X)
- Zhao Lin (ORCID: https://orcid.org/0000-0003-2567-627X)
- Zhao Huan
- Yi Pan (ORCID: https://orcid.org/0000-0001-8271-0521)
- Hanqi Jiang (ORCID: https://orcid.org/0009-0007-2778-959X)
- Longtao Yang
- Xin Zhang (ORCID: https://orcid.org/0000-0003-0047-3134)
- Wei Zhao (ORCID: https://orcid.org/0000-0002-8520-2087)
- Yuxiao Liu (ORCID: https://orcid.org/0009-0003-8298-5420)
- Yutong Zhang (ORCID: https://orcid.org/0009-0005-6190-1413)
Institutions
- Harvard University (US)
- Central South University (CN)
- University of Electronic Science and Technology of China (CN)
- Xinjiang Medical University (CN)
- University of Georgia (US)
- Northwestern Polytechnical University (CN)
- Fudan University (CN)
- WinnMed (US)
- ShanghaiTech University (CN)
- Massachusetts General Hospital (US)
- Shanghai University of Traditional Chinese Medicine (CN)
- Huadong Hospital (CN)
- First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
- The First People's Hospital of Changde (CN)
- Yueyang Second People's Hospital (CN)
- Yueyang Hospital (CN)
- Mayo Clinic in Florida (US)
- Second Xiangya Hospital of Central South University (CN)
- Second Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- IEEE Transactions on Biomedical Engineering
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1109/tbme.2025.3597325
- Citations
- 1
- Primary Topic
- Artificial Intelligence in Healthcare and Education
- Type
- article
- Field-Weighted Citation Impact
- 0.65