Mycobacterium tuberculosis curli pili facilitates pathogenicity by modulating central carbon metabolism
These novel findings show that MTP is associated with the regulation of bioenergetics and metabolism pathways and substantiate MTP as a potential biomarker for TB diagnostics/therapeutics, and a novel target for vaccine/drug development.
Authors
- Barry Truebody (ORCID: https://orcid.org/0000-0001-7066-3916)
- Jared S. Mackenzie (ORCID: https://orcid.org/0000-0002-3089-0900)
- Adrie J. C. Steyn (ORCID: https://orcid.org/0000-0001-9177-8827)
- Manormoney Pillay (ORCID: https://orcid.org/0000-0002-0253-479X)
- Shinese Ashokcoomar (ORCID: https://orcid.org/0000-0003-1537-3662)
- Tarien J Naidoo
Institutions
- University of Alabama at Birmingham (US)
- Africa Health Research Institute (ZA)
- University of KwaZulu-Natal (ZA)
Publication Details
- Journal
- Metabolomics
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1007/s11306-025-02320-5
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Inyuvesi Yakwazulu-Natali
- National Institutes of Health