No Evidence of Metabolomic Disruptions From Real‐World Intakes of Aspartame or Saccharin: The Coronary Artery Risk Development in Young Adults Study
In the largest metabolomics study to date, no link was found between metabolic disruptions and either aspartame or saccharin intake. We cannot exclude the possibility that more extreme intakes may be related to metabolic disruptions among consumers of artificial sweeteners.
Authors
- J. Jeffrey Carr (ORCID: https://orcid.org/0000-0002-4398-8237)
- Lyn M. Steffen (ORCID: https://orcid.org/0000-0002-4053-6729)
- Brian T. Steffen (ORCID: https://orcid.org/0000-0001-8010-2530)
- David R. Jacobs (ORCID: https://orcid.org/0000-0002-7232-0543)
- Elizabeth R. Lusczek (ORCID: https://orcid.org/0000-0003-4680-965X)
- James Greg Terry (ORCID: https://orcid.org/0000-0001-6659-3441)
- Linda Van Horn (ORCID: https://orcid.org/0000-0002-1362-5806)
- Venkatesh Locharla Murthy (ORCID: https://orcid.org/0000-0002-7901-1321)
- Chi Chen (ORCID: https://orcid.org/0000-0001-9703-604X)
Institutions
- Northwestern University (US)
- University of Minnesota (US)
- University of Michigan (US)
- Michigan Medicine (US)
- Minnesota Department of Health (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Journal of Diabetes
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1111/1753-0407.70138
- Primary Topic
- Biochemical Analysis and Sensing Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Northwestern University
- University of Minnesota
- National Heart, Lung, and Blood Institute