Investigation of MANF regulation of glioma stemness via STAT3/TGF-β/SMAD4/p38 pathway based on pan-cancer analysis
MANF emerges as a promising therapeutic target for glioma. This study clarifies MANF's specific mechanisms, offering insights into its potential for targeted glioma therapies.
Authors
- Shi Feng (ORCID: https://orcid.org/0000-0001-9084-3957)
- Fangfang Ding
- Ming Yang (ORCID: https://orcid.org/0000-0001-9843-3848)
- Hong Yang (ORCID: https://orcid.org/0000-0002-2847-668X)
- Pengfei Dong (ORCID: https://orcid.org/0000-0002-0954-8094)
- Xin Liu (ORCID: https://orcid.org/0000-0002-0011-6113)
- Huabao Cai
Institutions
- Hebei Medical University (CN)
- Anhui Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1016/j.tranon.2025.102497
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hebei Provincial Health and Family Planning Commission