Pre-admission Opioid Use and Associated Outcomes in Patients Revascularised for Lower Peripheral Artery Disease
This nationwide study identified a high risk subgroup of PAD patients with substantial opioid use and elevated mortality risk. Despite revascularisation, many with prior opioid use continued treatment post-discharge, highlighting the need for cautious prescribing and structured follow up to manage persistent pain and complex care needs. Although causality cannot be confirmed, pre-revascularisation opioid use was associated with a higher all cause mortality rate, probably reflecting greater disease severity.
Authors
- Lucas Grove Vejlstrup Bager (ORCID: https://orcid.org/0000-0002-9522-1580)
- Jeppe Kofoed Petersen (ORCID: https://orcid.org/0000-0002-1166-7877)
- Timothy Andrew Resch (ORCID: https://orcid.org/0000-0001-8407-8216)
- Lars Køber (ORCID: https://orcid.org/0000-0002-6635-1466)
- Kim G. Smolderen (ORCID: https://orcid.org/0000-0001-6104-6254)
- Carlos Mena‐Hurtado (ORCID: https://orcid.org/0000-0002-4954-5672)
- Emil Loldrup Fosbøl (ORCID: https://orcid.org/0000-0002-2048-4167)
- Jonas Eiberg (ORCID: https://orcid.org/0000-0002-7930-3842)
- Lauge Østergaard (ORCID: https://orcid.org/0000-0003-3298-1467)
Institutions
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Yale University (US)
- Copenhagen Academy for Medical Education and Simulation (DK)
Publication Details
- Journal
- European Journal of Vascular and Endovascular Surgery
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1016/j.ejvs.2025.08.026
- Citations
- 2
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 4.01