Circulating cytokine levels and 5-year vascular recurrence after stroke: A multicenter prospective cohort study
Among stroke patients, higher baseline levels of CD62E and MIF improved prediction of 5-year risk of recurrent stroke or TIA on top of vascular risk factors and CRP levels. Whether assessment of these cytokines could improve patient selection for secondary prevention trials of anti-inflammatory treatments, should be explored in future studies.
Authors
- Matthias Endres (ORCID: https://orcid.org/0000-0001-6520-3720)
- Inga Zerr (ORCID: https://orcid.org/0000-0002-6722-2463)
- Annika Spottke (ORCID: https://orcid.org/0000-0001-9854-2972)
- Gabor C. Petzold (ORCID: https://orcid.org/0000-0002-0145-8641)
- Christian H. Nolte (ORCID: https://orcid.org/0000-0001-5577-1775)
- Benno Ikenberg (ORCID: https://orcid.org/0000-0002-0798-7149)
- Felix J. Bode (ORCID: https://orcid.org/0000-0003-4498-186X)
- Mohamad Ali Antabi (ORCID: https://orcid.org/0000-0002-9903-1063)
- Omar El Bounkari (ORCID: https://orcid.org/0000-0002-3051-2096)
- Kathleen Bernkopf
- Sebastian Stösser (ORCID: https://orcid.org/0000-0002-1182-705X)
- Marios K. Georgakis (ORCID: https://orcid.org/0000-0003-3507-3659)
- Karin Waegemann
- Martin Dichgans (ORCID: https://orcid.org/0000-0002-0654-387X)
- Rong Fang (ORCID: https://orcid.org/0000-0002-5663-9407)
- Thomas Liman (ORCID: https://orcid.org/0000-0002-8471-8049)
- Daniel Janowitz (ORCID: https://orcid.org/0009-0003-4090-547X)
- Péter Hermann (ORCID: https://orcid.org/0000-0003-1889-8325)
- Silke Wunderlich (ORCID: https://orcid.org/0000-0003-1208-3686)
- Wenzel Glanz (ORCID: https://orcid.org/0000-0002-5865-4176)
- Jürgen Bernhagen (ORCID: https://orcid.org/0000-0003-2996-2652)
- João Mattar (ORCID: https://orcid.org/0000-0001-6265-6150)
- Lanyue Zhang (ORCID: https://orcid.org/0000-0002-6798-1320)
- Michael Görtler
Institutions
- Broad Institute (US)
- Carl von Ossietzky Universität Oldenburg (DE)
- University Hospital Bonn (DE)
- German Center for Neurodegenerative Diseases (DE)
- TUM Klinikum (DE)
- LMU Klinikum (DE)
- Munich Cluster for Systems Neurology (DE)
- Universitätsmedizin Göttingen (DE)
- German Centre for Cardiovascular Research (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Technical University of Munich (DE)
- Charité - Universitätsmedizin Berlin (DE)
- Ludwig-Maximilians-Universität München (DE)
- Otto-von-Guericke-Universität Magdeburg (DE)
Publication Details
- Journal
- European Stroke Journal
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1177/23969873251360145
- Citations
- 1
- Primary Topic
- Macrophage Migration Inhibitory Factor
- Type
- article
- Field-Weighted Citation Impact
- 0.80