Effects of aerobic and anaerobic exercise on glucose, lipid, and inflammation-related gene expression in the brain tissue of streptozotocin-induced diabetic rat model
This study revealed that exercise protocols of different intensities induce significant changes in the expression levels of some metabolic and inflammatory genes in brain tissue and decrease blood glucose levels in rats with streptozotocin-induced diabetes model. The findings suggest that exercise may partially modulate the molecular processes in the central nervous system of diabetes and may offer potential therapeutic contributions.
Authors
- Ragıp Pala (ORCID: https://orcid.org/0000-0002-3434-7462)
- Lütfiye Kadıoğlu Dalkılıç (ORCID: https://orcid.org/0000-0002-6791-3811)
- Emrah Özdemir (ORCID: https://orcid.org/0000-0003-4467-9919)
- Fatih Mehmet UĞURLU (ORCID: https://orcid.org/0000-0001-6830-4383)
- Yakup Kılıç (ORCID: https://orcid.org/0000-0003-4889-5571)
- Semih Dalkılıç (ORCID: https://orcid.org/0000-0002-6892-247X)
- Sezgin Hepsert
- Yeliz Ayyıldız
- Ercan Ayılgan
Institutions
- Koç University (TR)
- Fırat University (TR)
- Alanya University (TR)
- Ministry of Youth and Sports (RO)
- Alanya Alaaddin Keykubat Üniversitesi (TR)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1186/s13098-025-01893-4
- Citations
- 2
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.33