Therapeutic effects of topical Mycophenolate mofetil on hydroquinone-induced depigmentation in Guinea pigs and mice
MMF exhibits a notable capacity to ameliorate the pigment-loss effect associated with hydroquinone through the activation of the WNT signaling pathway. Consequently, MMF emerges as a promising therapeutic agent for mitigating skin pigmentation.
Authors
- Yifei Yang (ORCID: https://orcid.org/0000-0001-9817-484X)
- Yun Zhang
- Yuan Guo
- Yanhua-Li
- Haixia-Shi
Institutions
- Jiangsu University (CN)
- Affiliated Hospital of Jiangsu University (CN)
- Center for Neuroscience and Regenerative Medicine (US)
- Yangzhou University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1080/07853890.2025.2544880
- Citations
- 1
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- National Natural Science Foundation of China