Should Exogenous Ketone Body Supplementation Be Considered in Patients Hospitalized for Acute Heart Failure? Rationale and Design of the KETO-AHF Trial
The KETO-AHF trial will provide insights into the effects of supplementation with the ketone body 1,3-butanediol in patients hospitalized for AHF.
Authors
- Thomas Jensen (ORCID: https://orcid.org/0000-0002-5054-4108)
- Kristoffer Berg‐Hansen (ORCID: https://orcid.org/0000-0002-5110-0656)
- Johannes Grand (ORCID: https://orcid.org/0000-0002-5511-4668)
- Pardeep S. Jhund (ORCID: https://orcid.org/0000-0003-4306-5317)
- Morten Bøttcher (ORCID: https://orcid.org/0000-0002-2116-2370)
- Andreas Bugge Tinggaard (ORCID: https://orcid.org/0000-0003-2871-0584)
- Henrik Wiggers (ORCID: https://orcid.org/0000-0002-9753-4142)
- Søren Vraa
- Anders Hostrup Larsen (ORCID: https://orcid.org/0000-0003-1127-6910)
- Nigopan Gopalasingam (ORCID: https://orcid.org/0009-0006-6363-7406)
- Lisbeth Antonsen
- Mikael Kjær Poulsen (ORCID: https://orcid.org/0000-0003-4051-7197)
- Emil Wolsk (ORCID: https://orcid.org/0000-0002-6064-062X)
- Roni Nielsen (ORCID: https://orcid.org/0000-0001-9228-3869)
- Malene Hollingdal (ORCID: https://orcid.org/0000-0002-5891-0723)
- Toru Kondo (ORCID: https://orcid.org/0000-0001-6853-7574)
- Alexandre Mebazaa (ORCID: https://orcid.org/0000-0001-8715-7753)
- Morten Schou (ORCID: https://orcid.org/0000-0002-1274-5072)
- Jacob Eifer Møller (ORCID: https://orcid.org/0000-0003-2873-5845)
- Jens Dahlgaard Hove (ORCID: https://orcid.org/0000-0002-5600-5623)
- Niels Møller (ORCID: https://orcid.org/0000-0003-2128-4551)
- Barry A Borlaug
Institutions
- Mayo Clinic (US)
- Université Paris Cité (FR)
- Aalborg University Hospital (DK)
- Amager Hospital (DK)
- Odense University Hospital (DK)
- Hvidovre Hospital (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Gentofte Hospital (DK)
- Rigshospitalet (DK)
- Regionshospitalet Viborg (DK)
- Sorbonne Paris Cité (FR)
- Mayo Clinic Hospital (US)
- Nagoya University (JP)
- University of Glasgow (GB)
Publication Details
- Journal
- Journal of Cardiac Failure
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1016/j.cardfail.2025.07.013
- Citations
- 1
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Novo Nordisk Fonden