Comparative analysis of tumor and mesorectum radiomics in predicting neoadjuvant chemoradiotherapy response in locally advanced rectal cancer

Currently, the response of locally advanced rectal tumors to neoadjuvant therapy cannot be reliably predicted using conventional methods. Recently, the significance of the mesorectum in predicting treatment response has gained attention, although the number of studies focusing on this area remains limited. In our study, we performed radiomics analyses of both the tumor tissue and the mesorectum to predict neoadjuvant treatment response.

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Publication Details

Journal
Diagnostic and Interventional Radiology
Published
2025-08-12
DOI
https://doi.org/10.4274/dir.2025.253270
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
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article

Comparative analysis of tumor and mesorectum radiomics in predicting neoadjuvant chemoradiotherapy response in locally advanced rectal cancer

İlhan Öztop, Berke Manoğlu, Tayfun Bişgin, İlknur Bilkay Görken et al.
2 links
Diagnostic and Interventional Radiology
Colorectal Cancer Surgical Treatments
article

Comparative analysis of tumor and mesorectum radiomics in predicting neoadjuvant chemoradiotherapy response in locally advanced rectal cancer

İlhan Öztop, Berke Manoğlu, Tayfun Bişgin, İlknur Bilkay Görken, Ali Cantürk, Selman Sökmen, Funda Obuz, Özgül Sağol, Hakan Gülmez, Sülen Sarıoğlu, Kenan Kadirli, Raif Can Yarol, Ali Samet Tasak
article en

Abstract

Currently, the response of locally advanced rectal tumors to neoadjuvant therapy cannot be reliably predicted using conventional methods. Recently, the significance of the mesorectum in predicting treatment response has gained attention, although the number of studies focusing on this area remains limited. In our study, we performed radiomics analyses of both the tumor tissue and the mesorectum to predict neoadjuvant treatment response.

Diagnostic and Interventional Radiology
Ministry of Health (TR), Izmir University (TR), University of Health Science (KH), Dokuz Eylül University (TR), Memorial Sisli Hospital (TR), Sağlık Bilimleri Üniversitesi (TR), Turkish Society of Cardiology (TR), Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi (TR), University of Health Sciences Antigua (AG)
Good health and well-being
Openalex Percentile: Top 71%
Colorectal Cancer Surgical Treatments
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Comparative analysis of tumor and mesorectum radiomics in predicting neoadjuvant chemoradiotherapy response in locally advanced rectal cancer — İlhan Öztop, Berke Manoğlu, et al. · Diagnostic and Interventional Radiology (2025) | TGRS Research Map | TGRS