Immune Evasion Mechanism Mediated by ITPRIPL1 and Its Prognostic Implications in Glioma
This study reveals that ITPRIPL1 plays a dual role in glioma: It suppresses T cell-mediated immune responses, contributing to an immunosuppressive microenvironment, and interferes with the efficacy of antitumor drugs, thereby promoting tumor progression and ultimately leading to poor patient prognosis.
Authors
- Yuanyuan Yang (ORCID: https://orcid.org/0000-0003-1080-0135)
- Huan Wu (ORCID: https://orcid.org/0000-0002-0009-3839)
- Xiaoyun Zou
- Caiyun Ma
- Liu Changqing
- Yu Wenhao
- Wen Hebao
Institutions
- Bengbu Medical College (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/brb3.70762
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Natural Science Foundation of China