Oxytocin modulation of resting-state functional connectivity network topology in individuals with higher autistic traits
Overall, findings from this dimensional approach demonstrate that oxytocin particularly targets widespread enhancement of local but not global neural network processing parameters in neurotypical individuals with higher autistic traits. This suggests that intranasal oxytocin may represent a therapeutic option for social, emotional and sensorimotor symptoms in individuals with autism spectrum disorder by modulating local integration within brain regions involved in their regulation.
Authors
- Keith M. Kendrick (ORCID: https://orcid.org/0000-0002-0371-5904)
- Benjamin Klugah‐Brown (ORCID: https://orcid.org/0000-0002-3946-9557)
- Lei Xu (ORCID: https://orcid.org/0000-0001-9942-0117)
- Mercy Chepngetich Bore (ORCID: https://orcid.org/0000-0002-6438-3499)
- Jialin Li (ORCID: https://orcid.org/0000-0002-0310-904X)
- Xi Jiang (ORCID: https://orcid.org/0000-0003-3711-0847)
- Alice Hagan
- Benjamin Becker (ORCID: https://orcid.org/0000-0002-9014-9671)
- Juan Kou (ORCID: https://orcid.org/0000-0002-0634-7991)
- Yuan Hu (ORCID: https://orcid.org/0000-0003-2953-1545)
Institutions
- University of Electronic Science and Technology of China (CN)
- Sichuan Normal University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Psychoradiology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/psyrad/kkaf021
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China