Are chest X-rays still necessary for prebiologic tuberculosis screening? A retrospective audit

Biologic therapy is widely used in the UK for treating a wide range of autoimmune dermatological conditions if other treatments are not tolerated or are contraindicated. In the UK, it is common practice for chest X-rays (CXR) to be done with an interferon-γ release assay as part of the prebiologic tuberculosis (TB) screening. Studies have shown that CXR might not be effective in detecting latent or extrapulmonary TB. We report a single-centre retrospective audit of patients with hidradenitis suppurativa and psoriasis, which aimed to assess the value of CXR in screening TB before starting biologics.

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Publication Details

Journal
Clinical and Experimental Dermatology
Published
2025-08-08
DOI
https://doi.org/10.1093/ced/llaf378
Citations
1
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.52
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article

Are chest X-rays still necessary for prebiologic tuberculosis screening? A retrospective audit

Padma Mohandas, Mathina Darmalingam, Young-Hoon Kim, Daniel Yi Liang Tan
1 citations
Clinical and Experimental Dermatology
Lung Cancer Diagnosis and Treatment
1.52
article

Are chest X-rays still necessary for prebiologic tuberculosis screening? A retrospective audit

Padma Mohandas, Mathina Darmalingam, Young-Hoon Kim, Daniel Yi Liang Tan
article en
1 citations

Abstract

Biologic therapy is widely used in the UK for treating a wide range of autoimmune dermatological conditions if other treatments are not tolerated or are contraindicated. In the UK, it is common practice for chest X-rays (CXR) to be done with an interferon-γ release assay as part of the prebiologic tuberculosis (TB) screening. Studies have shown that CXR might not be effective in detecting latent or extrapulmonary TB. We report a single-centre retrospective audit of patients with hidradenitis suppurativa and psoriasis, which aimed to assess the value of CXR in screening TB before starting biologics.

Clinical and Experimental DermatologyVol. 51(1)
Barts Health NHS Trust (GB)
Good health and well-being
Openalex Percentile: Top 15%
Lung Cancer Diagnosis and Treatment
1.52
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