Intranasal Administration of KCNN2 Blocking Peptide Improves Deficits in Cognitive Flexibility in Mouse Model of Fetal Alcohol Spectrum Disorders
Intranasal administration of KCNN2 blockers, such as Lei-Dab7, represents a promising, non-invasive therapeutic approach for treating cognitive inflexibility and possibly other cognitive dysfunctions associated with FASD.
Authors
- Masaaki Torii
- Shahid Mohammad (ORCID: https://orcid.org/0000-0001-5239-7861)
- Kazue Hashimoto‐Torii (ORCID: https://orcid.org/0000-0003-4001-8259)
- Li Wang (ORCID: https://orcid.org/0000-0003-0036-3410)
Institutions
- Children's National (US)
- George Washington University (US)
Publication Details
- Journal
- The International Journal of Neuropsychopharmacology
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1093/ijnp/pyaf055
- Citations
- 1
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- National Institutes of Health
- Intellectual and Developmental Disabilities Research Center