Optimizing T cell transduction: a novel transduction device for efficient and scalable gene delivery
These findings suggest that TransB could significantly shorten the transduction time, reduce the transduction cost and improve the transduction efficiency for manufacturing genetically modified T cell therapies. It shows strong potential as a robust, efficient, and scalable platform to enhance T cell therapy manufacturing and help overcome current manufacturing challenges in the field.
Authors
- Tan Dai Nguyen (ORCID: https://orcid.org/0000-0002-8811-0014)
- Kang-Zheng Lee
- Liu Dan (ORCID: https://orcid.org/0000-0001-5128-6510)
Institutions
- Bioprocessing Technology Institute (SG)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1186/s12967-025-06836-1
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agency for Science, Technology and Research