Deep Learning Chest X-Ray Age, Epigenetic Aging Clocks and Associations with Age-Related Subclinical Disease in the Project Baseline Health Study
These results suggest that CXR-Age may serve as a better metric of cardiopulmonary aging than epigenetic aging clocks, especially in midlife adults.
Authors
- Douglas P. Kiel (ORCID: https://orcid.org/0000-0001-8474-0310)
- Adrian F. Hernandez (ORCID: https://orcid.org/0000-0003-3387-9616)
- Svati H. Shah (ORCID: https://orcid.org/0000-0002-3495-2830)
- Fátima Rodríguez (ORCID: https://orcid.org/0000-0002-5226-0723)
- Kenneth W. Mahaffey (ORCID: https://orcid.org/0000-0002-3791-2148)
- Jay Chandra (ORCID: https://orcid.org/0000-0002-1674-0180)
- David J. Maron (ORCID: https://orcid.org/0000-0002-4867-8588)
- Michael T. Lu (ORCID: https://orcid.org/0000-0003-4696-9610)
- Vineet K. Raghu (ORCID: https://orcid.org/0000-0003-3524-3945)
- Neha Jadeja Pagidipati (ORCID: https://orcid.org/0000-0002-5004-8868)
- Sarah Short
Institutions
- Brigham and Women's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Duke University (US)
- Cardiovascular Institute of the South (US)
- Gordon Center for Medical Imaging (US)
- Massachusetts General Hospital (US)
- Clinical Research Institute (US)
- VERN' University (HR)
- Hebrew SeniorLife (US)
- Stanford Medicine (US)
- Center for Clinical Research (United States) (US)
- Artificial Intelligence in Medicine (Canada) (CA)
- Stanford University (US)
Publication Details
- Journal
- The Journals of Gerontology Series A
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1093/gerona/glaf173
- Primary Topic
- Health, Environment, Cognitive Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00