Florfenicol sustained-release formulation does not promote resistance emergence in non-target bacteria: hollow-fibre infection studies with pig pathogens and commensals
The SR formulation of florfenicol showed equivalent efficacy to conventional dosing against key swine respiratory pathogens and posed minimal risk for selecting resistance in non-target E. coli. This supports the SR formulation as an effective single-dose alternative in veterinary practice.
Authors
- Stefano Azzariti (ORCID: https://orcid.org/0009-0007-9293-5266)
- Ludovic Pelligand (ORCID: https://orcid.org/0000-0001-6005-1975)
- Andrew Mead (ORCID: https://orcid.org/0000-0003-3550-3030)
- Pierre-Louis Toutain
- Abigail Hughes
Institutions
- Royal Veterinary College (GB)
- École Nationale Vétérinaire de Toulouse (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1093/jambio/lxaf200
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Royal Veterinary College