Genetically predicted iron status and cardiovascular function and structure: a Mendelian randomization study
Our study provides MR evidence that iron status may alter cardiovascular function and structure. HFE, TMPRSS6, TF and TFR2 genes play a crucial role in the identified associations.
Authors
- Luis Huicho (ORCID: https://orcid.org/0000-0002-5272-5885)
- Kim N. Cajachagua‐Torres (ORCID: https://orcid.org/0000-0002-0213-6935)
- Farnaz Khatami (ORCID: https://orcid.org/0000-0003-3589-1168)
- Taulant Muka (ORCID: https://orcid.org/0000-0003-3235-3073)
- Katerina Trajanoska (ORCID: https://orcid.org/0000-0002-3792-4296)
- Maryam Kavousi (ORCID: https://orcid.org/0000-0001-5976-6519)
- Michele F. Eisenga (ORCID: https://orcid.org/0000-0002-2484-6233)
- Hugo G. Quezada‐Pinedo (ORCID: https://orcid.org/0000-0002-0641-7718)
- Noushin Sadat Ahanchi (ORCID: https://orcid.org/0000-0003-2824-3648)
Institutions
- University of Bern (CH)
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Duke University (US)
- Universidad Peruana Cayetano Heredia (PE)
- Erasmus MC (NL)
- McGill Genome Centre (CA)
- Institute of Social and Preventive Medicine (CH)
- Erasmus MC - Sophia Children’s Hospital (NL)
- McGill University (CA)
- New York University (US)
- Tehran University of Medical Sciences (IR)
- Erasmus University Rotterdam (NL)
- University of Lausanne (CH)
Publication Details
- Journal
- European Journal of Preventive Cardiology
- Published
- 2025-08-04
- DOI
- https://doi.org/10.1093/eurjpc/zwaf498
- Citations
- 2
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.54