Low dose γ irradiation promotes the protective potential of <i>Syzgium aromaticum</i> flower buds extract in cisplatin-mediated nephrotoxicity via regulating Nrf-2/HO-1 and NF-κB/MAPK signaling pathways

Dual therapy of clove and LDR could be promising method for preventing cisplatin-nephrotoxicity and potentially enhancing the therapeutic index of cisplatin.

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Publication Details

Journal
International Journal of Radiation Biology
Published
2025-08-12
DOI
https://doi.org/10.1080/09553002.2025.2542324
Primary Topic
Chemotherapy-induced organ toxicity mitigation
Type
article
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article

Low dose γ irradiation promotes the protective potential of Syzgium aromaticum flower buds extract in cisplatin-mediated nephrotoxicity via regulating Nrf-2/HO-1 and NF-κB/MAPK signaling pathways

Esraa M. Samy, Marwa M. Elbatanony, Amal Mohamed El-Feky, Rasha R. Radwan et al.
International Journal of Radiation Biology
Chemotherapy-induced organ toxicity mitigation
article

Low dose γ irradiation promotes the protective potential of Syzgium aromaticum flower buds extract in cisplatin-mediated nephrotoxicity via regulating Nrf-2/HO-1 and NF-κB/MAPK signaling pathways

Esraa M. Samy, Marwa M. Elbatanony, Amal Mohamed El-Feky, Rasha R. Radwan, Heba Mohamed
article en

Abstract

Dual therapy of clove and LDR could be promising method for preventing cisplatin-nephrotoxicity and potentially enhancing the therapeutic index of cisplatin.

International Journal of Radiation BiologyVol. 101(10)
Egyptian Atomic Energy Authority (EG), National Research Centre (EG)
Zero hunger
Openalex Percentile: Top 71%
Chemotherapy-induced organ toxicity mitigation
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