Functional and internalizing disorders co-aggregate with cardiometabolic and immune-related diseases within families: a population-based cohort study
Internalizing and functional disorders share familial risk with immune-related and cardiometabolic diseases. This suggests that risk factors relevant to immune-related and cardiometabolic diseases may also be relevant for FDs. Future studies should investigate such risk factors to identify novel treatment targets.
Authors
- Judith G.M. Rosmalen (ORCID: https://orcid.org/0000-0002-6393-0032)
- Ilja M. Nolte (ORCID: https://orcid.org/0000-0001-5047-4077)
- Kenneth S. Kendler (ORCID: https://orcid.org/0000-0001-8689-6570)
- Sonja L. van Ockenburg (ORCID: https://orcid.org/0000-0002-7704-9959)
- Hanna M. van Loo (ORCID: https://orcid.org/0000-0002-9282-8053)
- Harold Snieder (ORCID: https://orcid.org/0000-0003-1949-2298)
- Olivier D. Steen (ORCID: https://orcid.org/0000-0002-6278-3106)
- Yiling Zhou (ORCID: https://orcid.org/0000-0001-6729-3627)
- M. Bos (ORCID: https://orcid.org/0000-0002-5288-2223)
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Virginia Commonwealth University (US)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-08-10
- DOI
- https://doi.org/10.1186/s12916-025-04293-7
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministerie van Volksgezondheid, Welzijn en Sport
- Universitair Medisch Centrum Groningen
- National Institute of Mental Health