Noggin alleviates neuropathic pain by regulating microglial polarization and remodeling iron homeostasis via a STAT3-dependent pathway.
NOG alleviates SNL-induced NP by antagonizing the STAT3 signaling pathway, thereby rebalancing microglial polarization and restoring iron metabolism.
Authors
- Ran Zhang
- Lin Yang (ORCID: https://orcid.org/0000-0002-9318-9812)
- Wenjuan Zhang (ORCID: https://orcid.org/0000-0002-9704-766X)
Institutions
- Central South University (CN)
- Hunan Normal University (CN)
- Changsha Normal University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-28
- DOI
- https://doi.org/10.11817/j.issn.1672-7347.2025.250206
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00