BTVT ameliorates offspring blood<b>-</b>brain barrier damage induced by prenatal and lactational neodymium oxide exposure via the gut<b>-</b>brain axis.
Maternal exposure to Nd<sub>2</sub>O<sub>3</sub> during pregnancy and lactation disrupts intestinal health and BBB integrity in offspring, elevates brain neodymium accumulation, and induces neuronal degeneration. BTVT effectively mitigates Nd<sub>2</sub>O<sub>3</sub>-induced intestinal and BBB damage in offspring, potentially through modulation of the gut-brain axis.
Authors
- Xiaowei Du (ORCID: https://orcid.org/0000-0003-2492-7591)
- Jianhong Cao (ORCID: https://orcid.org/0000-0002-9943-0312)
- Xiang Gao (ORCID: https://orcid.org/0000-0003-1885-2538)
- Lei Gao (ORCID: https://orcid.org/0000-0003-3916-6641)
- Sanping Zhao (ORCID: https://orcid.org/0000-0001-8124-2914)
- Xin Zhao (ORCID: https://orcid.org/0000-0001-9369-714X)
- Yang Deng (ORCID: https://orcid.org/0000-0002-4803-9014)
- Qingqing Liang
- Zhixin Huo
Institutions
- Baotou Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-28
- DOI
- https://doi.org/10.11817/j.issn.1672-7347.2025.250173
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00