Clinacanthus nutans (Burm.f.) Lindau facilitates cuproptosis and ameliorates colon cancer progression by inhibiting PDE3B-mediated Apelin pathway
Our study revealed CN delayed colon cancer by regulating PDE3B via suppression of the Apelin pathway, indicating the potential clinical relevance of CN in treating colon cancer.
Authors
- Zhiheng Lai
- Xuewu Chen (ORCID: https://orcid.org/0000-0002-2334-9702)
- Dan Su (ORCID: https://orcid.org/0000-0002-8423-1994)
- Lin Long
- Xueying Lin (ORCID: https://orcid.org/0000-0003-4180-2643)
- Gaoyun Zhou
Institutions
- Hainan Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1007/s12672-025-02037-w
- Citations
- 1
- Primary Topic
- Medicinal Plant Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.38