<scp>PFKFB3</scp> ‐Inhibitor <scp>3PO</scp> ‐Mediated Glycolytic Reprogramming Promotes Inflammatory Dental Pulp Repair: An In Vitro and In Vivo Study
The PFKFB3 inhibitor 3PO reduces inflammation and promotes reparative dentine formation in pulpitis via metabolic reprogramming and specific signalling pathways, offering a new therapeutic strategy.
Authors
- Ningxin Zhu (ORCID: https://orcid.org/0000-0003-0891-3042)
- Yijia Qiu
- Yuanyuan Wang (ORCID: https://orcid.org/0000-0003-1126-1639)
- Dan Wang (ORCID: https://orcid.org/0000-0002-5612-047X)
- Lixin Zhang (ORCID: https://orcid.org/0000-0003-0894-9520)
- Man Qin (ORCID: https://orcid.org/0000-0001-5791-3319)
- Yuqing Peng (ORCID: https://orcid.org/0000-0001-8201-143X)
- Fei Xie (ORCID: https://orcid.org/0000-0002-8764-8824)
- Yanqiang Zhao
- Jingyi Cui
Institutions
- King University (US)
- Peking University (CN)
- Peking University School and Hospital of Stomatology (CN)
Publication Details
- Journal
- International Endodontic Journal
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1111/iej.70016
- Citations
- 1
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Beijing Municipal Natural Science Foundation