Exploring the Molecular Features and Clinicopathological Correlations of Diffuse Sclerosing Papillary Thyroid Carcinoma
DSV-PTC demonstrates substantial molecular heterogeneity. RET fusions are linked to more aggressive behaviour, and paediatric cases often show extensive locoregional spread. Coexisting NTRK and TERT alterations may signal high-risk progression, highlighting the value of molecular stratification in management.
Authors
- Jianghua Wu (ORCID: https://orcid.org/0000-0001-7351-8933)
- Run-Fen Cheng
- Ying Wang (ORCID: https://orcid.org/0000-0002-1340-8422)
- Yanhui Zhang (ORCID: https://orcid.org/0000-0001-8277-8008)
- Tingting Ding (ORCID: https://orcid.org/0000-0003-2836-0086)
Institutions
- Peking University (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Clinical Endocrinology
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1111/cen.70013
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00