Efficacy of adjuvant nivolumab in patients with upper tract predominant urothelial carcinoma: A single-center real-world study

Adjuvant nivolumab was effective and well tolerated in Taiwanese patients with UTUC, resulting in promising DFS and OS. These findings suggest potential benefits of nivolumab in patients with UTUC. Further research on genomic and environmental influences and a prospective validation to refine patient selection for adjuvant immunotherapy are needed.

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Publication Details

Journal
Urologic Oncology Seminars and Original Investigations
Published
2025-08-09
DOI
https://doi.org/10.1016/j.urolonc.2025.07.014
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy of adjuvant nivolumab in patients with upper tract predominant urothelial carcinoma: A single-center real-world study

Jiun‐I Lai, Eric Yi‐Hsiu Huang, Tzu‐Ping Lin, Yi-Chieh Chen et al.
Urologic Oncology Seminars and Original Investigations
Bladder and Urothelial Cancer Treatments
article

Efficacy of adjuvant nivolumab in patients with upper tract predominant urothelial carcinoma: A single-center real-world study

Jiun‐I Lai, Eric Yi‐Hsiu Huang, Tzu‐Ping Lin, Yi-Chieh Chen, Ming Huang Chen, Tzu-Chun Wei, Hsiao‐Jen Chung, Yen-Hwa Chang, Peter Mu‐Hsin Chang, Chueh Chuan Yen
article en

Abstract

Adjuvant nivolumab was effective and well tolerated in Taiwanese patients with UTUC, resulting in promising DFS and OS. These findings suggest potential benefits of nivolumab in patients with UTUC. Further research on genomic and environmental influences and a prospective validation to refine patient selection for adjuvant immunotherapy are needed.

Urologic Oncology Seminars and Original InvestigationsVol. 43(12)
National Yang Ming Chiao Tung University (TW), Taipei Veterans General Hospital (TW)
Openalex Percentile: Top 67%
Bladder and Urothelial Cancer Treatments
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