Limited Prognostic Impact of Sustained Virologic Response on Atezolizumab plus Bevacizumab Therapy for HCV-Related Unresectable Hepatocellular Carcinoma
Although SVR was not independently associated with better survival, patients with SVR had preserved liver function and experienced fewer adverse events. These factors may indirectly support improved tolerability and therapeutic options during Atez/Bev therapy for HCV-related uHCC.
Authors
- Hideko Ohama (ORCID: https://orcid.org/0000-0002-1882-824X)
- Norio Itokawa (ORCID: https://orcid.org/0009-0002-2390-6692)
- Joji Tani (ORCID: https://orcid.org/0000-0001-8801-2505)
- Hironori Tanaka (ORCID: https://orcid.org/0000-0003-4712-0192)
- Kazunari Tanaka (ORCID: https://orcid.org/0000-0001-9811-2665)
- Yuki Kanayama (ORCID: https://orcid.org/0000-0002-8639-5212)
- Tomomitsu Matono
- Hidenao Noritake (ORCID: https://orcid.org/0000-0003-3649-5335)
- Kazuhito Kawata (ORCID: https://orcid.org/0000-0002-4986-8578)
- Kazuya Kariyama (ORCID: https://orcid.org/0000-0003-3996-7502)
- Hidenori Toyoda (ORCID: https://orcid.org/0000-0002-1652-6168)
- Hirayuki Enomoto (ORCID: https://orcid.org/0000-0003-1334-1149)
- Kazuhiro Nouso (ORCID: https://orcid.org/0000-0002-2018-0008)
- Hideyuki Tamai (ORCID: https://orcid.org/0000-0003-4511-4573)
- Takeshi Hatanaka (ORCID: https://orcid.org/0000-0003-3656-285X)
- Masatoshi Kudo (ORCID: https://orcid.org/0000-0002-4102-3474)
- Yoichi Hiasa (ORCID: https://orcid.org/0000-0003-4117-339X)
- Teruki Miyake (ORCID: https://orcid.org/0000-0002-9905-5356)
- Kunihiko Tsuji (ORCID: https://orcid.org/0009-0007-4152-9364)
- Atsushi Hiraoka (ORCID: https://orcid.org/0000-0003-1989-0480)
- Takashi Kumada (ORCID: https://orcid.org/0000-0003-2211-495X)
- Shinya Fukunishi (ORCID: https://orcid.org/0000-0001-6930-2814)
- Tomomi Okubo (ORCID: https://orcid.org/0000-0003-1244-4736)
- Takuya Nagano (ORCID: https://orcid.org/0000-0003-1043-8033)
- Ei Itobayashi (ORCID: https://orcid.org/0000-0003-0475-2819)
- Masaki Kaibori (ORCID: https://orcid.org/0000-0002-0577-3921)
- Masashi Hirooka (ORCID: https://orcid.org/0000-0001-5634-5313)
- Hiroki Nishikawa (ORCID: https://orcid.org/0000-0003-3489-2740)
- Hisashi Kosaka (ORCID: https://orcid.org/0000-0002-2926-9973)
- Kazuto Tajiri (ORCID: https://orcid.org/0000-0002-2373-8601)
- Takashi Nishimura (ORCID: https://orcid.org/0000-0002-5517-8303)
- Toshifumi Tada (ORCID: https://orcid.org/0000-0002-0976-6761)
- Atsushi Naganuma (ORCID: https://orcid.org/0000-0003-0663-0102)
- Hironori Ochi
- Akemi Tsutsui (ORCID: https://orcid.org/0000-0003-2978-2723)
- Hidekatsu Kuroda (ORCID: https://orcid.org/0000-0002-1471-1087)
- Toru Ishikawa (ORCID: https://orcid.org/0000-0002-5470-9694)
- Yutaka Yata (ORCID: https://orcid.org/0000-0002-4592-3509)
- Masanori Atsukawa (ORCID: https://orcid.org/0000-0003-3374-7111)
- Yuichi Koshiyama (ORCID: https://orcid.org/0009-0006-1247-1215)
- Tomoko Aoki (ORCID: https://orcid.org/0000-0002-9950-4553)
- Fujimasa Tada (ORCID: https://orcid.org/0009-0007-3964-5876)
- Asahiro Morishita (ORCID: https://orcid.org/0000-0002-0760-3045)
- Koichi Takaguchi (ORCID: https://orcid.org/0000-0003-0175-8721)
- Michitaka Imai (ORCID: https://orcid.org/0000-0001-6448-6036)
- Satoru Kakizaki (ORCID: https://orcid.org/0000-0003-0224-7093)
- Kosuke Matsui (ORCID: https://orcid.org/0000-0002-7274-0177)
- Shinichiro Nakamura (ORCID: https://orcid.org/0009-0001-5065-9669)
- Osamu Yoshida
- Taeang Arai
- Chikara Ogawa
Institutions
- Kansai Medical University (JP)
- Iwate Medical University (JP)
- Kagawa University (JP)
- Hamamatsu University School of Medicine (JP)
- Wakayama Rosai Hospital (JP)
- Takamatsu Red Cross Hospital (JP)
- Saiseikai Niigata Daini Hospital (JP)
- National Hospital Organization Takasaki Medical Center (JP)
- Matsuyama Red Cross Hospital (JP)
- Okayama Prefecture (JP)
- Ogaki Municipal Hospital (JP)
- Himeji Medical Center (JP)
- Hanwa Memorial Hospital (JP)
- Gunma Saiseikai Maebashi Hospital (JP)
- Himeji Red Cross Hospital (JP)
- Teine Keijinkai Hospital (JP)
- Asahi General Hospital (JP)
- Toyama University Hospital (JP)
- Ehime Prefectural Central Hospital (JP)
- Kagawa Prefectural Central Hospital (JP)
- Takarazuka City Hospital (JP)
- Ehime University (JP)
- Gifu Kyoritsu University (JP)
- Nippon Medical School (JP)
- Hyogo University (JP)
- Osaka University of Pharmaceutical Sciences (JP)
- Kindai University (JP)
Publication Details
- Journal
- Oncology
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1159/000547353
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00