The Role of Retinal Antigen-Presenting Cells in Spontaneous Retinal Autoimmunity
Our observations that local depletion of retinal APCs failed to inhibit SAU progression and that depletion of circulating APCs not only limited SAU progression but also, under defined circumstances, reduced clinical SAU support the idea that circulating APCs are crucial for the induction and progression of SAU.
Authors
- J.D. Sherman (ORCID: https://orcid.org/0000-0003-3956-6709)
- Dale S. Gregerson (ORCID: https://orcid.org/0000-0001-5769-796X)
- Scott W. McPherson (ORCID: https://orcid.org/0000-0003-4050-8805)
- Yunan Li (ORCID: https://orcid.org/0000-0001-7316-4354)
- Heidi Roehrich
- Laura Burgstaler
Institutions
- University of Minnesota (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1167/iovs.66.11.26
- Citations
- 1
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 1.71