Exploring Relationships Within the Microbiome of Root Canal Infections and the Influence of Associated Clinical Parameters
Despite critical gaps in root canal treatment clinical effectiveness, standardisation and understanding of pathogen complexity, our study, utilising next-generation 16S rRNA Sequencing and HOMINGS, provides valuable insights into core microbiome members involved in endodontic infections and their associations with distinct clinical signs and symptoms, offering insights that may guide more precise diagnosis and targeted treatment.
Authors
- Antônio Paulino Ribeiro Sobrinho (ORCID: https://orcid.org/0000-0002-3598-7592)
- Warley Luciano Fonseca Tavares (ORCID: https://orcid.org/0000-0003-2077-927X)
- Dana Mominkhan
- Lynn Martin
- Flavia Teles (ORCID: https://orcid.org/0000-0001-6945-9811)
- Abubakar Sadiq Yakubu (ORCID: https://orcid.org/0000-0002-5835-2186)
- Luciana Brito (ORCID: https://orcid.org/0000-0003-3378-7279)
- Eric B. Larson
- Michele Patel
Institutions
- Universidade Federal de Minas Gerais (BR)
- Harvard University (US)
- The University of Texas at San Antonio Health Science Center (US)
- The University of Texas at San Antonio (US)
- Universidade de Itaúna (BR)
- University of Pennsylvania (US)
Publication Details
- Journal
- International Endodontic Journal
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1111/iej.70011
- Citations
- 4
- Primary Topic
- Endodontics and Root Canal Treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.16
Funders
- University of Pennsylvania
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Universidade Federal de Minas Gerais