Family History of Hypertension Predicts Thyroid Cancer Risk in Women: A Population‐Based Cross‐Sectional Study With Integrative Machine Learning and Genomic Analyses
Our study provides novel clinical and genetic evidence that family history of hypertension is significantly associated with thyroid cancer in women. Integrating hypertension-related screening with genetic profiling may enhance risk stratification and aid in the development of personalized management strategies to reduce overtreatment.
Authors
- Fanke Meng
- Zijin Wang (ORCID: https://orcid.org/0000-0001-9158-4280)
- Zhengran Li (ORCID: https://orcid.org/0000-0002-9301-4430)
- Fanye Wu
- Yan‐Hui Lin (ORCID: https://orcid.org/0000-0001-6248-7537)
- Tong Wu (ORCID: https://orcid.org/0000-0003-3249-1812)
- Min Fu (ORCID: https://orcid.org/0000-0003-2638-1756)
- Zejun Chen (ORCID: https://orcid.org/0000-0002-7464-5122)
- Ziran Zhang (ORCID: https://orcid.org/0000-0002-7835-8788)
- Yuxin Sun (ORCID: https://orcid.org/0000-0002-6478-8234)
Institutions
- Central South University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Zhujiang Hospital (CN)
- Third Xiangya Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/cam4.71031
- Citations
- 3
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.88