Similar gout flare incidence rates when using once- or twice-daily 0.5 mg colchicine prophylaxis after the start of xanthine oxidase inhibitors

Colchicine prophylaxis 0.5 mg twice daily was not superior to colchicine once daily regarding flare prophylaxis after starting an XOI. As colchicine twice daily is associated with higher intolerability and costs, once-daily dosing should be preferred.

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Publication Details

Journal
Scandinavian Journal of Rheumatology
Published
2025-08-11
DOI
https://doi.org/10.1080/03009742.2025.2527462
Citations
1
Primary Topic
Gout, Hyperuricemia, Uric Acid
Type
article
Field-Weighted Citation Impact
1.43
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article

Similar gout flare incidence rates when using once- or twice-daily 0.5 mg colchicine prophylaxis after the start of xanthine oxidase inhibitors

Noortje van Herwaarden, Alfons A den Broeder, L. Nieboer, Frouwke Veenstra et al.
1 citations
Scandinavian Journal of Rheumatology
Gout, Hyperuricemia, Uric Acid
1.43
article

Similar gout flare incidence rates when using once- or twice-daily 0.5 mg colchicine prophylaxis after the start of xanthine oxidase inhibitors

Noortje van Herwaarden, Alfons A den Broeder, L. Nieboer, Frouwke Veenstra, Lise M Verhoef, Marcel Flendrie, Wing‐Yee Kwok
article en
1 citations

Abstract

Colchicine prophylaxis 0.5 mg twice daily was not superior to colchicine once daily regarding flare prophylaxis after starting an XOI. As colchicine twice daily is associated with higher intolerability and costs, once-daily dosing should be preferred.

Scandinavian Journal of RheumatologyVol. 54(6)
Radboud University Nijmegen (NL), University Medical Center (US), Radboud University Medical Center (NL), Sint Maartenskliniek (NL), Rijnstate Hospital (NL)
Good health and well-being
Openalex Percentile: Top 17%
Gout, Hyperuricemia, Uric Acid
1.43
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Similar gout flare incidence rates when using once- or twice-daily 0.5 mg colchicine prophylaxis after the start of xanthine oxidase inhibitors — Noortje van Herwaarden, Alfons A den Broeder, et al. · Scandinavian Journal of Rheumatology (2025) | TGRS Research Map | TGRS