Immunoinformatics study of CD40 ligand-targeting vaccine constructs: a novel immunotherapeutic approach
Overall, the CD40L multi-epitope vaccine construct demonstrated greater potency in eliciting an effective immune response than the full-length CD40L construct. These results highlight a promising approach to vaccine design for the prevention or treatment of infections and cancers.
Authors
- Fatemeh Heidarnejad (ORCID: https://orcid.org/0000-0003-1188-6356)
- Mahroo Mohamadi (ORCID: https://orcid.org/0000-0002-1283-0269)
- Hadi Bamehr
- Seyed Amir Sadeghi (ORCID: https://orcid.org/0000-0002-0213-1990)
- Azam Bolhassani (ORCID: https://orcid.org/0000-0001-7363-7406)
Institutions
- Pasteur Institute of Iran (IR)
- Biotechnology Research Center (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Osong Public Health and Research Perspectives
- Published
- 2025-08-11
- DOI
- https://doi.org/10.24171/j.phrp.2025.0077
- Citations
- 1
- Primary Topic
- vaccines and immunoinformatics approaches
- Type
- article
- Field-Weighted Citation Impact
- 0.81