A prognostic model for multiple myeloma based on lipid metabolism related genes.
LRGs serve as promising biomarkers for prognosis prediction and risk stratification in MM. The overexpression of chromosomal instability-related and high-risk genetic event-associated genes in high-risk patients may explain their poorer outcomes. Given the observed resistance to bortezomib and lenalidomide in high-risk patients, combination therapies involving BMS-754807 or I-BET-762 may represent effective alternatives.
Authors
- Zhengjiang Li (ORCID: https://orcid.org/0000-0002-6639-3420)
- Wen Zhou (ORCID: https://orcid.org/0000-0003-4085-7714)
- Fangming Shi
- Liang Zhao (ORCID: https://orcid.org/0000-0001-9915-7320)
- Jiaojiao Guo (ORCID: https://orcid.org/0000-0003-2110-8400)
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-28
- DOI
- https://doi.org/10.11817/j.issn.1672-7347.2025.240592
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00