Relationship between thromboembolic events and thrombopoietin receptor agonists: a pharmacovigilance analysis of the FDA Adverse Event Reporting System and the Japanese Adverse Drug Event Report
The study provided real-world evidence of TEE associated with TPO-RAs, highlighting a strong link despite variations in signal values and regional reporting practices. Findings underscore ongoing clinical safety surveillance for TPO-RAs.
Authors
- Changze Zhang
- Xijie Liao
- Zheng Wang (ORCID: https://orcid.org/0000-0001-7138-8581)
- Xiaojia Huang
- Yanqin Huang
- Liangping Yu
Institutions
- Zhongshan Hospital of Xiamen University (CN)
- Xiamen Chang Gung Hospital (CN)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1136/bmjopen-2025-099153
- Citations
- 1
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- U.S. Food and Drug Administration