Machine Learning Algorithm to Explore Patients With Heterogeneous Treatment Effects of Clinically Significant CMV Infection and Non‐Relapse Mortality After HSCT
A reliable, explainable, and interpretable ML model was developed to explore subpopulations with HTEs of csCMVi and NRM after HSCT. <b>Trial Registration</b>: The authors have confirmed clinical trial registration is not needed for this submission.
Authors
- Takashi Toya (ORCID: https://orcid.org/0000-0002-7436-972X)
- Masatsugu Tanaka (ORCID: https://orcid.org/0000-0001-8814-230X)
- Naoyuki Uchida (ORCID: https://orcid.org/0000-0001-5952-5926)
- Konan Hara (ORCID: https://orcid.org/0000-0003-1487-2638)
- Naoki Shingai
- Shuichi Ota (ORCID: https://orcid.org/0000-0002-3631-244X)
- Junya Kanda (ORCID: https://orcid.org/0000-0002-6704-3633)
- Y. Nakajima (ORCID: https://orcid.org/0000-0001-9317-6299)
- Satoshi Kaito (ORCID: https://orcid.org/0000-0001-7966-291X)
- Keisuke Kataoka
- Masao Ogata (ORCID: https://orcid.org/0000-0002-4896-5878)
- Satoshi Yoshihara (ORCID: https://orcid.org/0000-0002-8537-2422)
- Ayumi Taguchi
- Wataru Takeda
- Hiroyuki Ohigashi
- Tetsuya Eto
- Takahiro Fukuda
- Yukiyasu Ozawa
- Tetsuya Nishida
- Yuta Katayama
- Masashi Sawa
- Yoshiko Atsuta
- Satoru Takada
Institutions
- University of Arizona (US)
- Bunkyo University (JP)
- Aichi Medical University (JP)
- Oita University (JP)
- Keio University (JP)
- Kyoto University (JP)
- Kanagawa Prefectural Hospital Organization (JP)
- Tokyo Metropolitan Komagome Hospital (JP)
- Oita Medical Center (JP)
- Hamanomachi Hospital (JP)
- Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital (JP)
- Sapporo Hokuyu Hospital (JP)
- Japanese Red Cross Nagoya Daiichi Hospital (JP)
- Gunma Saiseikai Maebashi Hospital (JP)
- Hokkaido University Hospital (JP)
- Anjo Kosei Hospital (JP)
- The Japanese Data Center for Hematopoietic Cell Transplantation (JP)
- Toranomon Hospital (JP)
- Kanagawa Cancer Center
- Komazawa University (JP)
- Hyogo University (JP)
Publication Details
- Journal
- eJHaem
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/jha2.70117
- Citations
- 1
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Japan Agency for Medical Research and Development