Repurposing Asparaginase Therapy to Target Cisplatin‐Resistant Cancer Cells
Our results underpin the prevalence of altered metabolism in cisplatin-resistant cells and highlight the potential utility of re-purposing ASNase to target these cells, warranting further investigation.
Authors
- Sean G. Rudd (ORCID: https://orcid.org/0000-0002-4368-3855)
- Si Min Zhang (ORCID: https://orcid.org/0000-0001-7763-603X)
- J.S. Wang (ORCID: https://orcid.org/0000-0001-6397-9429)
- Jiří Bártek (ORCID: https://orcid.org/0000-0003-2013-7525)
- Robert Strauss (ORCID: https://orcid.org/0000-0003-1777-7177)
- Nasim Pouryaghoub
Institutions
- Sichuan University (CN)
- Science for Life Laboratory (SE)
- Karolinska Institutet (SE)
- West China Hospital of Sichuan University (CN)
- Danish Cancer Society (DK)
Publication Details
- Journal
- Fundamental and Clinical Pharmacology
- Published
- 2025-08-10
- DOI
- https://doi.org/10.1111/fcp.70044
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Åke Wiberg Stiftelse
- Kræftens Bekæmpelse
- Cancerfonden
- Karolinska Institutet
- Vetenskapsrådet
- Sichuan University
- Barncancerfonden
- Stiftelsen Clas Groschinskys Minnesfond
- West China Hospital, Sichuan University