A New Orthotopic Mouse Model of Laryngeal Squamous Cell Carcinoma
We have developed a novel and reproducible orthotopic mouse model, which more faithfully mimics the immune system response of the human body and better simulates the biological evolution process of tumors. This model provides an essential animal research framework for investigating the molecular mechanisms underlying the occurrence and development of laryngeal cancer.
Authors
- Hongxue Meng (ORCID: https://orcid.org/0000-0002-1831-2737)
- Ming Song (ORCID: https://orcid.org/0000-0001-7495-5895)
- Xionghui Mao
- Susheng Miao (ORCID: https://orcid.org/0000-0002-7701-9362)
- Lunhua Guo (ORCID: https://orcid.org/0009-0000-6062-3937)
- Jianfeng Chen (ORCID: https://orcid.org/0000-0002-8346-1173)
- Xueying Wang (ORCID: https://orcid.org/0000-0002-3026-052X)
- Junrong Wang (ORCID: https://orcid.org/0000-0001-7430-9308)
- Xianguang Yang (ORCID: https://orcid.org/0000-0002-7617-2816)
- Erliang Guo
- Lei Wang (ORCID: https://orcid.org/0009-0006-8680-3737)
Institutions
- Central South University (CN)
- Harbin Medical University (CN)
- Hunan University (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
- Laryngograph (United Kingdom) (GB)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Head & Neck
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1002/hed.70001
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Harbin Medical University
- National Natural Science Foundation of China
- Natural Science Foundation of Heilongjiang Province