Integrative approach for enhanced ovarian cancer diagnosis: cytology and biomarkers

Routine cytology effectively detects malignant cells in ovarian cancer serous effusions, while CA125 shows high sensitivity but limited standalone diagnostic value. LBC offers no additional advantage. CA125/CA153 combined testing significantly enhances diagnostic accuracy, particularly in advanced cases.

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Publication Details

Journal
Discover Oncology
Published
2025-08-10
DOI
https://doi.org/10.1007/s12672-025-03231-6
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrative approach for enhanced ovarian cancer diagnosis: cytology and biomarkers

Lei Cai, Shuangyan Chen, Yan Chen, Daoyin Zhou
Discover Oncology
Ovarian cancer diagnosis and treatment
article

Integrative approach for enhanced ovarian cancer diagnosis: cytology and biomarkers

Lei Cai, Shuangyan Chen, Yan Chen, Daoyin Zhou
article en

Abstract

Routine cytology effectively detects malignant cells in ovarian cancer serous effusions, while CA125 shows high sensitivity but limited standalone diagnostic value. LBC offers no additional advantage. CA125/CA153 combined testing significantly enhances diagnostic accuracy, particularly in advanced cases.

Discover OncologyVol. 16(1)
Second Military Medical University (CN), The First People's Hospital of Shunde (CN), Changhai Hospital (CN)
Good health and well-being
Openalex Percentile: Top 72%
Ovarian cancer diagnosis and treatment
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