Postoperative Infections and Antimicrobial Prophylaxis in the Pediatric Intensive Care Unit After Liver Transplantation in Children
One in five patients developed POI while in the PICU. Predictors of POI included younger age, open fascia, and hospitalization pre-transplantation. POIs were associated with significant morbidity, including prolonged length of stay, graft loss, and mortality. Future prospective studies are needed to optimize antimicrobial regimens to prevent POI and improve outcomes.
Authors
- Asumthia Jeyapalan (ORCID: https://orcid.org/0000-0001-7166-0725)
- Joseph Resch (ORCID: https://orcid.org/0000-0002-8204-3981)
- Kristina Betters (ORCID: https://orcid.org/0000-0002-3879-6660)
- Danielle Maue (ORCID: https://orcid.org/0000-0001-9875-0691)
- Mercedes Martínez (ORCID: https://orcid.org/0000-0001-6128-0155)
- Shubhi Kaushik (ORCID: https://orcid.org/0000-0003-1505-5322)
- Richard S. Mangus (ORCID: https://orcid.org/0000-0003-4300-2594)
- Paul K. Sue (ORCID: https://orcid.org/0000-0002-9750-9107)
- Elise Kang (ORCID: https://orcid.org/0000-0002-4189-6697)
- Michael Nares (ORCID: https://orcid.org/0009-0003-5746-2177)
- Leslie Ridall
- Sameer Kamath (ORCID: https://orcid.org/0000-0001-6280-7473)
- Matt S. Zinter (ORCID: https://orcid.org/0000-0003-3351-3278)
- Alicia M. Alcamo (ORCID: https://orcid.org/0000-0002-5406-5681)
- Fernando Beltramo
- Alexandra Monde
- Courtney Marie Rowan (ORCID: https://orcid.org/0000-0003-1393-6476)
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- University of Minnesota (US)
- Montefiore Medical Center (US)
- Children's Hospital of Philadelphia (US)
- Children's Hospital of Los Angeles (US)
- University of Miami (US)
- Duke University (US)
- University of California, San Francisco (US)
- Georgetown University (US)
- Vanderbilt University (US)
- Columbia University Irving Medical Center (US)
- Mount Sinai Medical Center (US)
- Indiana University Bloomington (US)
- Duke University Hospital (US)
- Indiana University (US)
- University of Colorado Denver (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Pediatric Transplantation
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1111/petr.70158
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- NHLBI Division of Intramural Research