Substantia Nigra Hyperechogenicity Predicts Parkinson's Disease Risk in Patients With Essential Tremor and Undetermined Tremor: Dual‐Cohort Longitudinal Evidence With 8‐Year Follow‐Up and Bayesian Validation
TCS-detected SN+ is a predictor of PD progression over 8 years in both ET and UT cohorts. The consistent risk association across tremor subtypes in SN+ subgroups supports its clinical potential as a cross-tremor subtype biomarker.
Authors
- Xianglin Qu
- Lijuan Wang (ORCID: https://orcid.org/0000-0002-5439-8988)
- Jie Zhang (ORCID: https://orcid.org/0000-0001-8719-698X)
- Ying Liu (ORCID: https://orcid.org/0000-0002-9977-1600)
- Yan‐Li Gao (ORCID: https://orcid.org/0000-0001-9052-012X)
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1111/ene.70326
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Jilin Province
- People's Government of Jilin Province
- Jilin University
- First Hospital of Jilin University