Intraocular Pressure After Anti-Vascular Endothelial Growth Factor Injection in Eyes With a Mineralized Bruch's Membrane Caused by Pseudoxanthoma Elasticum
The time to restore to baseline IOP after anti-VEGF injection is longer in PXE patients. Given the early need for anti-VEGF treatment, frequent injections, and the possible heightened vulnerability (e.g., optic disc drusen) in PXE patients, clinical trials on pre-injection IOP-lowering measures warrant consideration.
Authors
- Karl Mercieca
- Maximilian Pfau (ORCID: https://orcid.org/0000-0001-9761-9640)
- Frank Gerhard Holz (ORCID: https://orcid.org/0000-0001-8019-9272)
- Jeannette Ossewaarde‐van Norel (ORCID: https://orcid.org/0000-0003-2864-6025)
- Petrus Chang (ORCID: https://orcid.org/0000-0002-0071-3452)
- Redmer van Leeuwen (ORCID: https://orcid.org/0000-0002-9007-7276)
- Kristina Pfau (ORCID: https://orcid.org/0000-0002-3642-3502)
- Kristin Raming (ORCID: https://orcid.org/0000-0003-1133-8675)
- Sara Risseeuw (ORCID: https://orcid.org/0000-0002-2970-797X)
- Thomas Ach (ORCID: https://orcid.org/0000-0001-6583-8283)
- Philipp Herrmann
- Jonathan Meinke
- Isabel Saltenberger
Institutions
- Roche (Switzerland) (CH)
- University of Bonn (DE)
- Utrecht University (NL)
- University Hospital of Basel (CH)
- University Medical Center Utrecht (NL)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1167/iovs.66.11.25
- Primary Topic
- Dermatological and Skeletal Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft