Macular microvascular alterations in adults with sickle cell anemia detected by optical coherence tomography angiography

Sickle cell anemia is associated with substantial microvascular compromise in the deep retinal capillary plexus, even in the absence of clinical retinopathy. OCTA proves to be a sensitive, non-invasive imaging modality capable of detecting subclinical vascular changes. Early identification of these alterations may aid in the prevention of vision-threatening complications in SC anemia.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-08-09
DOI
https://doi.org/10.1016/j.pdpdt.2025.104759
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
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OCT
article

Macular microvascular alterations in adults with sickle cell anemia detected by optical coherence tomography angiography

Sevgi Polat Bağcıer, Esra Vural, Leyla Hazar, Çağrı Mutaf
Photodiagnosis and Photodynamic Therapy
Hemoglobinopathies and Related Disorders
article

Macular microvascular alterations in adults with sickle cell anemia detected by optical coherence tomography angiography

Sevgi Polat Bağcıer, Esra Vural, Leyla Hazar, Çağrı Mutaf
article en

Abstract

Sickle cell anemia is associated with substantial microvascular compromise in the deep retinal capillary plexus, even in the absence of clinical retinopathy. OCTA proves to be a sensitive, non-invasive imaging modality capable of detecting subclinical vascular changes. Early identification of these alterations may aid in the prevention of vision-threatening complications in SC anemia.

Photodiagnosis and Photodynamic TherapyVol. 55
Dicle University (TR), Kırklareli University (TR), Istanbul Eye Hospital (TR), Dünyagöz Hospital (TR), Harran University (TR)
Good health and well-being
Openalex Percentile: Top 72%
Hemoglobinopathies and Related Disorders
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Macular microvascular alterations in adults with sickle cell anemia detected by optical coherence tomography angiography — Sevgi Polat Bağcıer, Esra Vural, et al. · Photodiagnosis and Photodynamic Therapy (2025) | TGRS Research Map | TGRS