SPINT1-AS1 promotes oxidative damage and apoptosis of gastric cancer cells via the miR-656-3p/PLCXD3 axis

SPINT1-AS1 suppresses GC malignancy through the regulation of the miR-656-3p/PLCXD3 axis. These findings provide robust data supporting the biological functions of lncRNAs in GC and offer potential targets for therapeutic intervention.

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Publication Details

Journal
Discover Oncology
Published
2025-08-09
DOI
https://doi.org/10.1007/s12672-025-03195-7
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.00
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article

SPINT1-AS1 promotes oxidative damage and apoptosis of gastric cancer cells via the miR-656-3p/PLCXD3 axis

Xiaohui Wei, Xin Zhao, Song Li, XU Duo et al.
1 links
Discover Oncology
Cancer-related molecular mechanisms research
article

SPINT1-AS1 promotes oxidative damage and apoptosis of gastric cancer cells via the miR-656-3p/PLCXD3 axis

Xiaohui Wei, Xin Zhao, Song Li, XU Duo, Tong Wu
article en

Abstract

SPINT1-AS1 suppresses GC malignancy through the regulation of the miR-656-3p/PLCXD3 axis. These findings provide robust data supporting the biological functions of lncRNAs in GC and offer potential targets for therapeutic intervention.

Discover OncologyVol. 16(1)
Shanxi Medical University (CN), Weinan Normal University (CN), Chongqing Jiulongpo People's Hospital (CN), Shanxi Provincial People’s Hospital (CN)
Good health and well-being
Openalex Percentile: Top 74%
Cancer-related molecular mechanisms research
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