Identifying Predictors for Heart Failure Outcomes in Phospholamban p.(Arg14del)–Positive Individuals
This study identified predictors for heart failure outcomes in PLN p.(Arg14del)-positive individuals that can improve risk prediction. Identifying those at risk for heart failure outcomes is of great importance given the rapid advancements in genetic therapies that may offer potential treatments for hereditary cardiomyopathy.
Authors
- Karin Y. van Spaendonck‐Zwarts
- Arthur A.M. Wilde (ORCID: https://orcid.org/0000-0002-0528-0852)
- Laurens P. Bosman (ORCID: https://orcid.org/0000-0002-7847-4607)
- Arjan C. Houweling (ORCID: https://orcid.org/0000-0002-7728-7535)
- Freyja H.M. van Lint (ORCID: https://orcid.org/0000-0002-1787-4519)
- Virginnio Proost (ORCID: https://orcid.org/0000-0002-2658-3385)
- Juan Ramón Gimeno (ORCID: https://orcid.org/0000-0001-5818-1754)
- M Heide (ORCID: https://orcid.org/0009-0009-0251-7760)
- Remco de Brouwer (ORCID: https://orcid.org/0000-0002-5705-2034)
- Rudolf A. de Boer (ORCID: https://orcid.org/0000-0002-4775-9140)
- Laura M G Meems (ORCID: https://orcid.org/0000-0001-8627-7139)
- Ahmad S. Amin (ORCID: https://orcid.org/0000-0002-1600-7907)
- Tom E. Verstraelen (ORCID: https://orcid.org/0000-0002-4340-6815)
- Aeilko H. Zwinderman (ORCID: https://orcid.org/0000-0003-0361-3139)
- Esmée van Drie (ORCID: https://orcid.org/0000-0002-6278-0626)
- Moniek G.P.J. Cox (ORCID: https://orcid.org/0000-0003-2825-8428)
- Tjeerd Germans (ORCID: https://orcid.org/0000-0003-2781-0145)
- B. A. Schoonderwoerd
- J Peter van Tintelen
- Cathelijne Dickhoff
- Anneline S J M Te Riele
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Erasmus MC (NL)
- Medisch Centrum Leeuwarden (NL)
- University Medical Center Utrecht (NL)
- Noordwest Ziekenhuisgroep (NL)
- Netherlands Heart Institute (NL)
- ERN GUARD-Heart (NL)
- Westfriesgasthuis (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- JACC Heart Failure
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1016/j.jchf.2025.102558
- Citations
- 2
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Bristol-Myers Squibb
- AstraZeneca
- Alnylam Pharmaceuticals
- Boston Scientific Corporation
- Amsterdam University Medical Centers
- Fondation Leducq
- ZonMw
- Universitair Medisch Centrum Utrecht
- Universitair Medisch Centrum Groningen