Development and validation of a risk prediction model for venous thromboembolism after surgery in elderly patients with lung cancer

The incidence of postoperative VTE in elderly lung cancer patients is relatively high. Key risk factors include an extremely high-risk Caprini score, surgical duration ≥ 120 min, open surgery, clinical stage III-IV disease, preoperative chemotherapy, positive D-D>3.64 mg/L, and elevated CRP levels. The nomogram-based risk prediction model developed in this study exhibits high discrimination and accuracy, with good predictive ability and clinical utility, providing a basis for targeted prevention and management strategies.

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Publication Details

Journal
BMC Surgery
Published
2025-08-09
DOI
https://doi.org/10.1186/s12893-025-03080-8
Citations
2
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
3.74
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article

Development and validation of a risk prediction model for venous thromboembolism after surgery in elderly patients with lung cancer

Xiangmei Zhang, Qing Lin, Bingrui Xu, Jie Luo et al.
2 citations
BMC Surgery
Venous Thromboembolism Diagnosis and Management
3.74
article

Development and validation of a risk prediction model for venous thromboembolism after surgery in elderly patients with lung cancer

Xiangmei Zhang, Qing Lin, Bingrui Xu, Jie Luo, Shuqian Wang, Lijun Chen, Shi Wang
article en
2 citations

Abstract

The incidence of postoperative VTE in elderly lung cancer patients is relatively high. Key risk factors include an extremely high-risk Caprini score, surgical duration ≥ 120 min, open surgery, clinical stage III-IV disease, preoperative chemotherapy, positive D-D>3.64 mg/L, and elevated CRP levels. The nomogram-based risk prediction model developed in this study exhibits high discrimination and accuracy, with good predictive ability and clinical utility, providing a basis for targeted prevention and management strategies.

BMC SurgeryVol. 25(1)
First Affiliated Hospital of Xiamen University (CN)
Openalex Percentile: Top 6%
Venous Thromboembolism Diagnosis and Management
3.74
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Development and validation of a risk prediction model for venous thromboembolism after surgery in elderly patients with lung cancer — Xiangmei Zhang, Qing Lin, et al. · BMC Surgery (2025) | TGRS Research Map | TGRS