Cholesterol homeostasis and pathway enrichment in post-revascularization recovery
This exploratory study provides preliminary evidence that heart revascularization may affect cholesterol-related metabolic pathways. While the small sample size (n = 4 revascularized patients) limits generalizability, these findings generate important hypotheses regarding post-revascularization metabolic adaptation and establish a foundation for larger validation studies. Future research with expanded cohorts is essential to confirm these preliminary observations and their therapeutic implications.
Authors
- Syed Abdullah Basit
- Nehad M. Alajez (ORCID: https://orcid.org/0000-0002-1546-1091)
- Tanvir Alam (ORCID: https://orcid.org/0000-0001-7033-3693)
Institutions
- Hamad bin Khalifa University (QA)
- Qatar Foundation (QA)
Publication Details
- Journal
- BioMedical Engineering OnLine
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1186/s12938-025-01429-x
- Primary Topic
- Cholesterol and Lipid Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hamad Bin Khalifa University
- Khalifa University of Science, Technology and Research
- College of Science and Engineering, University of Minnesota