Cholesterol homeostasis and pathway enrichment in post-revascularization recovery

This exploratory study provides preliminary evidence that heart revascularization may affect cholesterol-related metabolic pathways. While the small sample size (n = 4 revascularized patients) limits generalizability, these findings generate important hypotheses regarding post-revascularization metabolic adaptation and establish a foundation for larger validation studies. Future research with expanded cohorts is essential to confirm these preliminary observations and their therapeutic implications.

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Publication Details

Journal
BioMedical Engineering OnLine
Published
2025-08-09
DOI
https://doi.org/10.1186/s12938-025-01429-x
Primary Topic
Cholesterol and Lipid Metabolism
Type
article
Field-Weighted Citation Impact
0.00

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article

Cholesterol homeostasis and pathway enrichment in post-revascularization recovery

Syed Abdullah Basit, Nehad M. Alajez, Tanvir Alam
BioMedical Engineering OnLine
Cholesterol and Lipid Metabolism
article

Cholesterol homeostasis and pathway enrichment in post-revascularization recovery

Syed Abdullah Basit, Nehad M. Alajez, Tanvir Alam
article en

Abstract

This exploratory study provides preliminary evidence that heart revascularization may affect cholesterol-related metabolic pathways. While the small sample size (n = 4 revascularized patients) limits generalizability, these findings generate important hypotheses regarding post-revascularization metabolic adaptation and establish a foundation for larger validation studies. Future research with expanded cohorts is essential to confirm these preliminary observations and their therapeutic implications.

BioMedical Engineering OnLineVol. 24(1)
Hamad bin Khalifa University (QA), Qatar Foundation (QA)
Hamad Bin Khalifa University, Khalifa University of Science, Technology and Research, College of Science and Engineering, University of Minnesota
Good health and well-being
Openalex Percentile: Top 67%
Cholesterol and Lipid Metabolism
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