Analysis of surgical margins in breast cancer patients undergoing mastectomy in Tanzania

This study revealed a high rate of margin positivity following mastectomy, largely driven by advanced tumor stage and young age at presentation. To improve surgical outcomes in low-resource settings, we recommend interventions to improve earlier diagnosis and expanded use of neoadjuvant therapy for patients with locally advanced disease.

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Publication Details

Journal
BMC Surgery
Published
2025-08-09
DOI
https://doi.org/10.1186/s12893-025-03118-x
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Analysis of surgical margins in breast cancer patients undergoing mastectomy in Tanzania

A. Amin, Larry Akoko, Nashivai Kivuyo, Zephania Gega
BMC Surgery
Breast Cancer Treatment Studies
article

Analysis of surgical margins in breast cancer patients undergoing mastectomy in Tanzania

A. Amin, Larry Akoko, Nashivai Kivuyo, Zephania Gega
article en

Abstract

This study revealed a high rate of margin positivity following mastectomy, largely driven by advanced tumor stage and young age at presentation. To improve surgical outcomes in low-resource settings, we recommend interventions to improve earlier diagnosis and expanded use of neoadjuvant therapy for patients with locally advanced disease.

BMC SurgeryVol. 25(1)
Muhimbili University of Health and Allied Sciences (TZ), Muhimbili National Hospital (TZ), Ocean Road Cancer Institute (TZ)
Muhimbili University of Health and Allied Sciences, University of Health and Allied Sciences
Good health and well-being
Openalex Percentile: Top 74%
Breast Cancer Treatment Studies
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