Functional mechanism and clinical implications of lncRNA NEAT1 in traumatic fractures and their correlation with delayed healing
lncRNA NEAT1 expression was up-regulated in DFH patient serum, and it has high diagnostic value for delayed fracture healing. lncRNA NEAT1 targeting miR-654-3p affected the activity and apoptosis of osteogenic differentiated cells.
Authors
- Meng Han
- Qianqian Cheng (ORCID: https://orcid.org/0000-0002-9204-3707)
- Hongqing Wang (ORCID: https://orcid.org/0000-0002-2977-7732)
- Hua Meng (ORCID: https://orcid.org/0000-0002-4712-8365)
- Zhaoyu Chen (ORCID: https://orcid.org/0000-0002-7112-2596)
- Yue Shang (ORCID: https://orcid.org/0000-0003-4121-2029)
- Shenyi Lu
Institutions
- Hebei Medical University (CN)
- Peking University (CN)
- Beijing Tian Tan Hospital (CN)
- Xingtai People's Hospital (CN)
- Peking University People's Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1186/s13018-025-06152-w
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87