NLR Risk Score for Predicting Patient Prognosis in Hepatocellular Carcinoma and Identification of Oncogenic Role of NLRP5 in Hepatocellular Carcinoma
This study developed an NLR-based prognostic model that effectively stratifies HCC patients by survival risk. NLRP5 was identified as a novel oncogene promoting HCC progression via the p53 pathway, suggesting its potential as a therapeutic target.
Authors
- Ting Wu (ORCID: https://orcid.org/0000-0002-1806-3056)
- Qinglei Kong (ORCID: https://orcid.org/0000-0002-5515-3683)
- Lifen Hu
- Yanyan Liu (ORCID: https://orcid.org/0000-0002-0535-2369)
- Mimi L.K. Tang (ORCID: https://orcid.org/0000-0002-3839-5293)
- Cui Wang (ORCID: https://orcid.org/0000-0003-0276-2538)
- W. Sun (ORCID: https://orcid.org/0000-0001-5260-658X)
- Yufeng Gao (ORCID: https://orcid.org/0000-0002-5837-3382)
- Qingyue Zhang (ORCID: https://orcid.org/0000-0002-4193-7428)
- Shengfu He (ORCID: https://orcid.org/0009-0008-3069-1160)
- Chengcheng Li (ORCID: https://orcid.org/0000-0001-7511-9311)
- Jiabin Li
- Bao Meng (ORCID: https://orcid.org/0000-0001-6509-8721)
- Yating Sun (ORCID: https://orcid.org/0009-0000-6446-1525)
- Qinxiu Xie
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.32604/or.2025.067065
- Citations
- 1
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.32