Distinct Metabolic and Inflammation Signatures in Urban vs Rural Ugandan Youth With HIV on Dolutegravir
The monocyte activation marker sCD14, was associated with HIV status and remained elevated in rural YPHIV even after adjusting for differences in HIV factors. Increasing the inclusion of rural populations in sub-Saharan Africa is paramount as we focus on preventing comorbidities in aging YPHIV.
Authors
- Grace A. McComsey (ORCID: https://orcid.org/0000-0003-2690-8888)
- Kate Ailstock
- Nicholas Funderburg (ORCID: https://orcid.org/0000-0003-3113-1217)
- Victor Musiime (ORCID: https://orcid.org/0000-0001-7472-9054)
- M.J. Cummings
- Robert Kidega (ORCID: https://orcid.org/0009-0004-5283-2148)
- Rashida Nazzinda
- Cissy Kityo (ORCID: https://orcid.org/0000-0002-9286-7052)
- Sahera Dirajlal‐Fargo (ORCID: https://orcid.org/0000-0001-9945-9062)
- Christine Karungi (ORCID: https://orcid.org/0000-0002-8475-3397)
- Shan Sun (ORCID: https://orcid.org/0000-0002-9087-4101)
- Nina Lucas
- Daisy Faith Oryem
Institutions
- Northwestern University (US)
- Ohio Department of Health (US)
- Lurie Children's Hospital (US)
- Joint Clinical Research Centre (UG)
- The Ohio State University (US)
- Case Western Reserve University (US)
- Makerere University (UG)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-07-18
- DOI
- https://doi.org/10.1093/ofid/ofaf420
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Norges Idrettshøgskole
- National Institutes of Health
- Clinical and Translational Science Collaborative of Cleveland, School of Medicine, Case Western Reserve University
- National Center for Advancing Translational Sciences